Anand B K & Brobeck J R. Hypothalamic control of food intake in rats and cats. Yale J. Biol. Med. 24:123-40, 1951
ثبت نشده
چکیده
Bilateral destructions of a well localised area in lateral hypothalamus led to complete cessation of eating, while lesions involving ventromedial nuclei or the region between these and lateral area produced hyperphagia and obesity. The lateral region (hunger mechanism) was designated 'feeding center' and the medial (inhibitory control) 'satiety center.' [The SCI indicates that this paper has been cited over 400 times since 1961.]
منابع مشابه
Hypothalamic Control of Food Intake in Rats and Cats *
Marked variations in food intake have been described in various species following injury to certain parts of the hypothalamus, including an increased food intake or hyperphagia caused by lesions in the medial hypothalamus, especially lesions in or ventrolateral to the ventromedial nucleus; this hyperphagia leads to obesity."1418' 20 24 A decrease or complete inhibition of food intake has also b...
متن کاملHypothalamic control of food intake in cats and monkeys.
The role of the central nervous system in regulating food intake was probably suggested first by the discovery that either obesity or emaciation may occur in patients with nervous diseases. For a while these observations were not properly evaluated, because emphasis was laid upon the obesity as such, or the leanness, rather than upon the changed eating habits responsible for the clinical pictur...
متن کاملNeural and hormonal mechanisms regulating food intake.
In this outline of the neural control of food intake, no attempt has been made to provide a comprehensive survey of the literature since there are several symposia and reviews available which summarize the extensive work in this field (Grossman, 1975; Novin et al. 1976; Silverstone, 1976; Morgane & Panksepp, 1980; Hoebel & Novin, 1982). Instead some current concepts of the neural control of foo...
متن کاملThe effects of lateral hypothalamic lesions on food intake and instrumental alimentary reflex in dogs.
Since Anand and Brobeck (1951) localized the "feeding center" in the lateral hypothalamus, the role of hypothalamic structures in alimentary mechanisms has been studied by many investigators (Teitelbaum and Stellar 1954, Miller 1957, Wyrwicka 1957, Chereshniev 1960, Morgane 1961a, Teitelbaum and Epstein 1962, Balinska 1963, Balinska and Brutkowski 1967, Wyrwicka 1967ab and others). Most of the ...
متن کاملبررسی تاثیر هشت هفته تمرینات متوسط و شدید بر سطوح پلاسمایی نوروپپتید Y و هورمون گرلین در رتهای چاق نژاد اسپراگو- داولی
Background and Objective: Exercise and physical activity are the most impressive factors in consumption of cellular energy sources which may bring about some changes in key peptides that are effective in adjusting and balancing energy. The purpose of this study was to investigate the probable changes of plasma Neuropeptide Y (NPY) and Ghrelin concentrations after 8 weeks of exercise with differ...
متن کامل